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Catalyst Health Ventures
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About CHV

Investing in the future of MedTech

About CHV

About CHV

We have a long history of focusing on the fast-growing MedTech sector and a proven track record of backing successful entrepreneurs transforming healthcare through innovation. We look for investment opportunities where we can identify value early and where we see the potential to fundamentally transform patient outcomes.

Our investment philosophy is rooted in deep collaboration – with founders, management teams, and syndicate partners – to build successful companies. We work closely with our portfolio companies, providing guidance, support, and access to our expansive network. We strongly believe that no two investments are the same and support the most suitable business and financing model for each venture. We help founders to build a syndicate of investors who bring complementary relationships and a shared vision for the future.

Meet Our Team

Investment Strategy

Focus

Within the broader healthcare market, we focus our investments on medical technologies including therapeutic and technology-enabled devices, digital health, and diagnostic devices that enhance patient outcomes. We have backed both first-time and experienced founders, who value our perspective as well as our capital.

Stage

Stage

As life cycle investors, we partner with companies at critical inflection points and often serve as their first institutional investor. We make our first investment at the seed through Series B stages, often timed to align with the transition from pre-clinical to clinical development, where risk is minimized and opportunities for meaningful value creation are highest. We support companies through product development and clinical milestones along the often complex regulatory process.

Capital

Capital Efficiency

We focus on businesses with a disciplined approach to resource allocation, emphasizing lean development and strategic prioritization. Our goal is to back teams that can achieve key milestones efficiently, maximizing value creation and setting the stage for successful exits.

Therapeutic Indications

We seek out companies addressing significant unmet clinical needs in large, global markets, with a clear potential to transform patient outcomes. We are agnostic to specific therapeutic areas, and are particularly drawn to high-value medical devices that have the potential to drive meaningful impact on healthcare.

Testimonials

Building several companies teaches you the value of working with investors who show up consistently, especially when things get hard. What sets Josh and CHV apart is their long-term mindset and steadfast support — they stay engaged through every stage, always ready to roll up their sleeves and add value far beyond the check. It’s rare to find that kind of alignment and perseverance.
Sameer SabirCo-Founder & CEO, Brixton Biosciences, Founder, EyeCool Therapeutics
As a founder focused on the detection of ovarian cancer, having a partner who truly understood the problem made all the difference. Darshana’s early confidence and unwavering support were instrumental in transforming our idea into a clinical trial and, ultimately, a successful acquisition by a major MedTech company.
Surbhi SarnaCEO & Founder, nVision Medical
As a serial founder, I have had the opportunity to work with many investors and Darshana and the CHV team stand out. They have backed me in three companies now, and each time they bring more than just capital – they bring deep conviction, steady guidance, and a collaborative mindset. They are the kind of investor you want in your corner, no matter how many times you do this.
Amar SawhneyCEO & Founder, Augmenix, Instylla, CEO, Rejoni
Raising a Series A financing in the toughest financial environment in recent memory was a significant challenge. Josh believed in us when others didn't. He led our financing and helped us complete syndication by introducing us to the right MedTech partners. His dedication, commitment and patience made all the difference in getting us off the ground. Working with Josh is a true partnership; he collaboratively guides and backs management teams in growing their businesses. He is exactly the person you want to build a company with.
Aditya RajagopalCEO, Chairman & Co-Founder, Esperto Medical
What stands out about Darshana and CHV is they take the time to understand your vision and challenges, provide level-headed guidance through the ups and downs, and were proactive in making the right introductions that were instrumental in helping us close our round. That combination of support, collaboration, and network is exactly what early-stage founders need.
Erik van der BurgCo-Founder, Director & CEO, Venova Medical
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Our Team

Our team has worked together for over a decade to build a portfolio of innovative and impactful companies

Meet Our Team